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会場青葉山キャンパス 工学研究科機械・知能系内 
医療工学21COE/REDEEM棟 講堂
Lecture 1 (15:30-16:30):

Bionics Research in KIST (Korea Institute of Science & Technology)

Dr. Kuiwon Choi
(Biomedical Research Center, Korea Institute of Science and Technology)

In this presentation, the bionics research as a national agenda project in Korea will be introduced. Since 2007, KIST has started to find out future research topics as a leading government institute in Korea. A committee for the future convergence technology has been formed as well as a consulting from outside KIST has been received. Bionics research was selected the first research area KIST should start. Bionics area is too broad and wide, therefore, KIST needed to focus a selective area where fundamental technologies would be produced. Implantable electrodes systems for human-machine interfaces are chosen for next 5 years projects. The current research trends and clinical applications of electrode systems will be introduced and KIST electrode research projects will be presented in detail.

Lecture 2 (16:30-17:30):

Polymer Nanotechnology for Optical Molecular Imaging

Dr. Ick Chan Kwon
(Biomedical Research Center, Korea Institute of Science and Technology)

In recent years, advances in medical imaging technology have been emphasized along with new advances in the field of cellular and molecular biology. Emerging field of medical imaging, i.e. Molecular Imaging, allows not a traditional image of anatomical changes, but a biological characterization of disease state at molecular or cellular lever. Interdisciplinary research at the interface of nanotechnology and molecular imaging had led to elucidate key factors that determine specificity in diagnosis and therapeutics. For example, with combining molecular imaging technology and drug delivery system, a novel design of drug screening or new approaches in drug development can be performed in animal models. Polymer nanoparticles bearing near-infrared fluorescent dyes can be utilized in determining optimized therapeutic dosages or frequencies of drug administration. These nanoparticles also can be utilized as molecular probes for visualization of therapeutic efficacy in small animals. Design of novel polymeric nanoparticles with high specificity in cellular or molecular responses, application of molecular imaging probes toward the era of Personalized Medicine will be presented in current study.

[1] Park, K. et al, New generation of multifunctional nanoparticles for cancer imaging and therapy, 2009 Advanced Functional Materials 19 (10), pp. 1553-1566
[2] Lee, S. et al, Activatable imaging probes with amplified fluorescent signals, 2008 Chemical Communications (36), pp. 4250-4260
[3] Lee, S. et al, A near-infrared-fluorescence-quenched gold-nanoparticle imaging probe for in vivo drug screening and protease activity determination, 2008 Angewandte Chemie - International Edition 47 (15), pp. 2804-2807
[4] Park, J.H. et al, Polymeric nanomedicine for cancer therapy, 2008 Progress in Polymer Science (Oxford) 33 (1), pp. 113-137
[5] Kim, J.H. et al, Protein-phosphorylation-responsive polymeric nanoparticles for imaging protein kinase activities in single living cells, 2007 Angewandte Chemie - International Edition 46 (30), pp. 5779-5782
[6] Kim, J.H. et al, Polymers for bioimaging, 2007 Progress in Polymer Science (Oxford) 32 (8-9), pp. 1031-1053
[7] Kim, K et al, Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging, 2006 Journal of the American Chemical Society 128 (11), pp. 3490-3491
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